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NHQLiveTM Label-Free and High Content Live Cell Imaging Analyzer ≫

NHQLive™ is an imaging analyzer integrating multimodal imaging, automated operation and intelligent analysis. Based on label-free imaging, NHQLive™ is additionally equipped with environmental control and automatic acquisition functions required for cell culture, making it possible to observe the physiological state of live cells in real time. The product has a built-in LFAI™ (Label-free AI) software, which further improves the efficiency of imaging analysis.

 

NHQLive™ greatly frees up hands, simplifies imaging steps, accelerates imaging and analysis processes, and becomes an important tool for observing and understanding biological phenomena.
Multimodal Imaging

Label-free quantitative phase imaging
Four-channel fluorescence imaging
Next-generation bright-field solutions

Automation

Automatic positioning and focusing
Large field of view stitching
Long-term live cell imaging

AI-empowered

Dynamic cell capture
Instant image-to-data conversion
One-click intelligent analysis

Streamlined, Flexible, and Intelligent: Fully Meet Imaging Needs

Label-Free — Presenting Cells in Their Most Authentic State

NHQLive™ integrates advanced label-free optical technology — interferometric quantitative phase imaging technology. it measures the phase delay imparted by the sample to the incident light to generate high-contrast quantitative phase images without using markers, accurately presenting the dynamic changes of samples.

User Benefits:

  • Authentic Restoration: Image biological samples directly without using exogenous dyes or markers.
  • Efficient Imaging: Achieve ultra-fast imaging to meet the needs of high-sensitivity experiments.
  • Rich Biological Information: Obtain new information such as cell dry weight, mechanical properties, and density distribution by analyzing phase distribution.

Study on the surface vibration of red blood cell membranes (iQPM)

Multimodal Imaging — Flexibly Choose the Most Suitable Imaging Channel

NHQLive™ integrates transmitted light and fluorescence imaging modes, providing 6 imaging options, including quantitative phase imaging, bright-field imaging, and four fluorescence channels (DAPI, FITC, TRITC, Cy5).

User Benefits:

  • Convenient switching of imaging modes: Switch between bright-field, quantitative phase, and fluorescence anytime and anywhere without moving samples to other systems.
  • Multi-channel cell fusion: Support multi-channel cell fusion to obtain multi-parameter indicators, providing comprehensive data support for experiments.

Bovine aortic endothelial cells treated with DAPI (nuclear dye), coralite488-phalloidin (cytoskeleton dye), mitotracker red (mitochondrial dye), and DiD (cell membrane dye); Objective lens: 40X

Long-Term Observation of Live Cells — Capture the Natural Dynamics of Cells

NHQLive™ can be equipped with an incubation system, providing environmental control, automatic acquisition, and intelligent analysis functions to support long-term continuous monitoring of live cells.

User Benefits:

  • Climate control function: The entire enclosed internal sample space can be climate-controlled (temperature and carbon dioxide regulation), ensuring cells grow and undergo experiments in the most suitable environment.
  • Bright and comfortable experimental environment: Say goodbye to dim experimental spaces and improve laboratory work efficiency and comfort.

Continuous 25-hour imaging of human articular chondrocytes

Streamlined Workflow — Simplify Imaging and Analysis Processes

NHQLive™ is equipped with LFAI™ (Label-free AI) software, which realizes full automation of complex image acquisition and analysis processes through precise algorithms.

User Benefits:

  • Simplified imaging process: Automated operations such as automatic focusing, automatic image scanning and analysis, and automatic control of Time-lapse imaging reduce operating steps by more than 50%.
  • AI image analysis: LFAI™ has a built-in data analysis software empowered by AI, realizing functions such as cell segmentation, tracking, classification, counting, and morphological analysis, improving the efficiency of image analysis.

NHQLive™ Application Scenarios

The era of label-free high content imaging has arrived!

The future is here — enjoy the innovative experience.

Accessories

Stage Upgrade Solution

Upgrade to XY motorized stage
High precision and compact structure
Support scanning strokes for 2-4 slides

Incubator

Intensive design for easier operation
Can hold slides and multi-well plates
High-precision control of CO₂, temperature, and humidity

Microfluidic Module

Applicable for cell culture
Cell counting
High-throughput cell detection

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